Diastolic Dysfunction
Cardiac Diastole was long ignored as all the attention was focused on cardiac systole. Diastole is an active process comprising of isovolumic relaxation, early diastolic filling, diastasis in mid-diastole and atrial contraction resulting in last minute ventricular filling before systole starts. It is a period of rest and relaxation for the heart.
Prevalence of diastolic dysfunction can range from mild to moderate to severe progressing to diastolic heart failure. Incidence varies from 33-50% above age of 50 years with high 5 year mortality of above 50%
There are various echo parameters available to assess diastolic function and these include size of LA, LV isovolumic relaxation time (IVRT), Mitral deceleration time (DT), Mitral flow velocity (E), E at A velocity. , Peak mitral A velocity and A wave duration, study of pulmonary venous flow pattern and color flow mitral propagation velocity and derived PCWP.
These indices give a fair assessment of type and degree of diastolic dysfunction to help plan appropriate medical therapy.