Ultrasound Guided Liver Biopsy in Hepatitis C patients.Comparison with Serum ALT, Biopsy Result and Color Doppler Findings

  • Dr Asim Shaukat, Punjab Medical College/Allied Hospital, Faisalabad, Pakistan
  • Prof Mehdi Rizvi, Punjab Medical College/Allied Hospital,Faisalabad, Pakistan
  • Purpose
    To compare the findings of Liver histopathology , color Doppler findings and blood enzymes, with Liver histopathology as the gold standard
    Material and Methods
    This study was conducted in the Department of Radiology Punjab Medical College , Allied Hospital , Faisalabad Pakistan, from January 2007 till September 2008 , in which 150 patients with Hepatitis C were first examined through Color Doppler ultrasound , their Liver function tests were done and then Ultrasound guided Liver Biopsy was done.


    Results & Conclusion
    Comparison of results were done between the
    • Color Doppler ultrasound findings, namely , Liver texture , margins, Portal vein diameter, Portal vein velocity , Hepatic vein pattern , Hepatic artery velocity , Spleen length &
    • LFTs , mainly ALT &
    • Liver Histopathology results, which was taken as gold standard

    showed that there is close resemblance to Liver Histopathological scoring and splenic length , Hepatic veins pattern shows some correlation and portal vein velocity has also certain association with liver cirrhosis due to Hepatitis C related Liver diseases. SGPT has limited relation to the stage of the disease.
    We want to present our study and its results in your esteemed Conference.