Objective: To detect cardiac function in rabbits models with ischemic reperfusion and to evaluate the short-term protective effects of ischemic postconditioning on regional systolic function of left ventricle by echocardiography.
Methods: Twenty-eight rabbits were divided into 2 groups: control and ischemic postconditioning. Echocardiography were performed before tests and 2 weeks after tests. The conventional echocardiography indices included LVDd, AW and LVEF. QTVI and SRI indices included the peak velocity in systole (Vs) and radial peak strain rate in systole (SRs) .
Results: Before tests, there were no difference in conventional echocardiography indices between the two groups; compared with before test, the two groups had significantly larger LVDd, thiner AW and lower LVEF(p<0.05); compared with the controls, the group IP had significantly smaller LVDd, thicker AW and higher LVEF 2 weeks after tests(p<0.05); compared with controls, the number of segments with abnormal wall motion in group IP significantly decreased. Before tests, there were no difference in Vs and radial SRs between the two groups; compared with before test, the two groups had significantly lower Vs and radial SRs(p<0.05); compared with the controls, Vs and radial SRs in group IP significantly increased 2 weeks after tests(p<0.05).
Conclusions: Ischemic postconditioning can protect regional systolic function of rabbits models with ischemic reperfusionin in short-term, which can be effectively evaluated by SRI .