Objective: To evaluate the value of strain rate imaging (SRI) quantitative detecting regional and global function of left ventricular (LV) in patients with hypertrophic cardiomyopathy (HCM).
Methods: 33 patients with HCM, who were divided into 3 groups by thickness of interventriclar septum and left ventricular posterior wall, that was: 1non hypertrophy, NH;2mild hypertrophy, MH; 3severe hypertrophy, SH; 31 controls were performed echo examination. Flow propagation velocity (FPV)were measured. The indies included: peak strain rate in early diastole (SRe) , peak strain rate in late diastole (SRa) and SRe /SRa .
Results: Compared with controls, SRe and SRe /SRa of the three groups of HCM decreased significantly, and NH>MH>SH; compared with controls, SRa of MH and SH decreased significantly, but there was no difference between NH and controls, and NH>MH>SH; compared with NH and MH, SRe /SRa of SH decreased significantly, but there was no significant difference of SRe /SRa between NH and MH; Compared with controls, mean SRe and SRe /SRa of all segments in patients with HCM decreased significantly; mean SRe and SRe /SRa of all segments in patients with HCM significantly correlated with FPV(r=0.75 and r=0.70, seperately); but there was no correlation between SRa and FPV.
Conclusions: The regional and global diastolic function of LV in patients with HCM damaged with or without hypertrophy, and can be evaluated quantitatively, accurately by SRI.