The Application of Contrast-Enhanced Ultrasound in the Diagnosis of Renal Mass Lesions

  • Dr Lian-fang Du, First People's Hospital affiliated Shanghai Jiao Tong University, China
  • Dr Fan Li, First People′s Hospital affiliated Shanghai Jiao Tong University, China
  • Ying Wu, First People′s Hospital affiliated Shanghai Jiao Tong University, China
  • Ying-qian He, First People's Hospital affiliated Shanghai Jiao Tong University, China
  • Dr Yang Zhou, Nan Chong Medical College, China
  • Dr Yunfei Ma, First People's Hospital affiliated Shanghai Jiao Tong University, China
  • Dr Huiping Zhang, First People′s Hospital affiliated Shanghai Jiao Tong University, China

    • Purpose: To explore the value of ultrasound contrast agent Sonovue and cadence contrast pulse sequencing technology(CPS,Siemens)in renal occupied lesions.
    Methods: 361 suspected renal occupied lesions underwent conventional and contrast-enhanced ultrasound examinations.
    Equipment: Sequoia512; contrast agent: 0.8ml ~ 1.2ml Sonovue; injection mode: 5ml 0.9% NaCl injection just after bolus injection of Sonovue via peripheral vein. To assess the perfusion time and its characteristic of the agent,the results were compared with that of pathology.
    Results: In the 361 lesions, 275 lesions were diagnosed as malignant: 216 lesions presented with fast and high enhancement in cortex phase, 37 with slow enhancement, 22 with iso-enhancement; 69 with quick wash-out, 167 with slow wash-out, 39 with iso-wash-out. 86 lesions were diagnosed as benign: periphery of the 18 lesions presented with fast enhancement in renal cortex phase, 26 with slow enhancement, 21 with inhomogenous enhancement, 21 with no enhancement.
    Pathology results: malignant 252, begine 109 .clear cell carcinoma 210 , clear cell sarcoma 3, squamous cell carcinoma 4, multilocular cystic renal carcinoma 3 , papillary renal cell carcinoma 10,chromophobe carcinoma 8,granular cell carcinoma 3, Bellini carcinoma 2,metastatic carcinoma 5, non-Hodgkin′s limphoma in 4. The accuracy,sensitivity,and specificity were 91.6%(252/275), 78.8%(86/109), 94.0%(361/384), respectively.
    Conclusion: The contrast-enhanced ultrasound has significant value in the differential diagnosis of the renal occupied lesions.