Objective: To compare the diagnosis value of real-time sonoelastography and mammography in breast lesions.
Methods: The instrument furnish used is the HITACH EUB 8500, Equipped with 7.5-13MHz high frequency linear- array transducer. 83 female patients including 101 lesions of breast disease were studied with color Doppler flow image and real-time sonoelastography. All cases were performed mammography,then verified by operation and Pathology. The target lesion was scored as 1 to 5, using the scoring system proposed by Itoh. The accuracy of sonoelastography and mammography for diagnosing breast diseases was compared. Receiver operating characteristic curves(ROC) were used to assess the diagnostic value of sonoelastography.
Results: The sensitivity /specificity/accuracy of the aonoelastography diagnostic method were 87.06%/ 93.05%/91.08% respectively, of mammography were 72.4%,83.33%,80.19%. The positive and negetive-likelihood ratio for sonoelastography was 12.41(95%CI,5.90 to 26.88)and 0.14(95%CI,0.06 to 0.30); for mammography, was 4.34(95%CI,1.63-11.42)and 0.33(95%CI,0.19-0.63).
Conclusions: Sonoelastography and mammography were both effective technology in the diagnosis of breast lesions. Sonoelastography has higher diagnostic value than mammography in breast lesions, especially,in the lesions which were no calcification. To combine sonoelastography with mammography can elevate the accuracy differentiating the benign from malignant breast lesions.