Aim. To consider the role of ultrasound in predicting therapeutic efficiency of thyroid benign cystic lesions with aspirations and Levothyroxin
Method and Subjects. The longitudinal and prospective study. The sample included 74 subjects ( 16-70 of age ) who were taken Doppler ultrasound, FNAC, blood tests for thyroid function. All were treated with fluid aspirations and Levothyroxin in combination, and followed monthly during 6 months.
Results. The rates of therapeutic response and recurrence in general were 77% ( 57 cases ) and 23% ( 17 cases ) in respectively. These rates in subjects having thin, smooth and thick, irregular margin were 87.5% vs 12.5% and 44.4% vs 55.6%, not having and having solid component were 79.7% vs 20.3%, and 40% vs 60% in respectively ( p<0.05 ). The recurrence rates of lesions with the largest diameter over 32mm were higher than of lesions below 27mm ( p<0.05 ). Moreover, the response rates were higher in subjects having dilute aspirated fluid ( 85.7% ) compared with condense fluid ( 50% ) ( p<0.05 ), and in cases the first aspirated volume percentage over 75% of initial volume ( p< 0.05 ).
Conclusion. There were significant relations between therapeutic response possibility and characters of margin, solid component existence, the largest diameter, aspirated fluid viscosity, first aspirated volume percentage of thyroid benign cystic lesions.