Ultrasonography of Hepatic Lymphoma
Background/Aims: Lymphoma, especially primary hepatic lymphoma is a rare entity in hepatic malignancy. Few studies discuss this tumor. We present our observations concerning the ultrasonography of hepatic lymphoma. Method: From January 2002 to May 2007, three hundred and nine lymphoma cases were diagnosed in our hospital. Of them, ten hepatic lymphoma cases (three primary) were diagnosed with pathologic proof. We reviewed their medical record and compared their abdominal ultrasound. Results: The abdominal ultrasound revealed nodular lesion with variable number and size and hypo or mixed in echogenicity, located in either lobe or both lobes. Central necrosis was noted in one case with large tumor (>15cm). Primary hepatic lymphoma was single and iso to mixed type echoic nodule. Secondary hepatic lymphoma was usually multiple and hypo echoic nodules. Computed tomography revealed low density on the non-enhanced phase and heterogeneous poor enhancement on post-contrast phase. Magnetic resonance imaging revealed high signal intensity on T2-weighted image, and low signal intensity on T1-weighted image with heterogeneous enhancement on contrast study. Conclusion: The ultrasonographic characteristics of hepatic lymphoma are variable in size and number. They are usually hypoechoic. The vascular pattern is different from hepatocellular carcinoma. It is important to make a differential diagnosis by Doppler, even contrast enhanced Doppler ultrasound.