Application of Time –Intensity Curve of Contrast-Enhanced Ultrasonography in the Diagnosis of Breast Masses

  • Yuan Zhang, Department of ultrasound, Pudong New District Hospital ,Shanghai, China
  • Quan Jiang, Pudong New District Hospital, China
  • Jian Chen, Department of ultrasound, Pudong New District Hospital ,Shanghai 201200,China, China

    • Objective: To discuss the diagnostic value of time-intensity curve analysis contrast –enhanced ultrasonography (CEUS) in the diagnosis of breast masses.
    Methods: Totally ,49 patients with breast masses (22 benign ,27 malignant )were examined with CEUS.SonoVue was used as a contrast media .The dynamic CEUS images were analyzed with the time-intensity curve software .
    Results: After contrast agent injection ,high enhancement cases in malignant group were more than those in benign group .The correlation between benign and malignant lesions was stastically significant (P <0.05).There was statistical difference between breast benign and malignant tumors in configuration and parameters on time-intensity curve .The arrival time and the time to peak enhancement were shorter in malignant group than those in benign group (P <0.05) .The slope of the rising part and peak intensity was greater in malignant than that in benign group (P <0.05).
    Conclusion: Time-intensity curve analysis of contrast-enhanced ultrasonography is helpful in differentiating diagnosis of breast masses.